Survival of Nematode Larvae Strongyloides papillosus and Haemonchus contortus under the Influence of Various Groups of Organic Compounds

Many chemically synthesized xenobiotics can significantly inhibit the vitality of parasitic nematodes. However, there is yet too little research on toxicity such contaminating compounds toward Compounds that are present in plants able to organisms as well. According results our laboratory studies toxicity, following caused no decrease larvae Strongyloides papillosus and Haemonchus contortus: methanol, propan-2-ol, propylene glycol-1,2, octadecanol-1, 4-methyl-2-pen-tanol, 2-ethoxyethanol, butyl glycol, 2-pentanone, cyclopentanol, ortho-dimethylbenzene, dibutyl phthalate, succinic anhydride, 2-methylfuran, 2-methyl-5-nitroimidazole. Strong towards nematode was exerted by glutaraldehyde, 1,4-diethyl 2-methyl-3-oxobutanedioate, hexylamine, diethyl malonate, allyl acetoacetate, tert carboxylic acid, acrylate, 3-methyl-2-butanone, isobutyraldehyde, methyl ethyl pyruvate, 3-methylbutanal, cyclohexanol, cyclooctanone, phenol, pyrocatechin, resorcinol, naphthol-2, phenyl ether, piperonyl alcohol, 3-furoic maleic anhydrid, 5-methylfurfural, thioacetic butan-1-amine, dimethylformamide, 1-phenylethan-1-amine, 3-aminobenzoic acid. Widespread natural (phytol, 3-hydroxy-2-butanone, oleic hydroquinone, gallic acid-1-hydrate, taurine, 6-aminocaproic glutamic carnitine, ornithine monohydrochloride) had negative effect S. H. contortus. A powerful produced 3,7-dimethyl-6-octenoic isovaleric glycolic 2-oxopentanedioic 2-methylbutanoic anisole, 4-hydroxy-3-methoxybenzyl furfuryl alcohol. The allow us consider 28 62 we studied promising for further anti-nematode activity manufacturing conditions.